Chlorhexide Sensitivity Information

The risk is low.

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The estimated incidence of chlorhexidine-induced anaphylaxis was 0.78 per 100,000 exposures.¹*

*According to the Royal College of Anaesthetists' allergen survey conducted in 2018.

Have a patient with a suspected chlorhexidine allergy?

Below are suggestions for how to manage patients with this type of condition.

Emphasize taking patient history and reviewing anesthesia records
Perform proactive chlorhexidine allergy tests
For patients with a confirmed allergy, provide an allergy card or bracelet for easy identification and avoid chlorhexidine-containing drugs or medical devices

Determined Commitment

Teleflex strives to be your trusted vascular access partner, working with you to provide accurate and relevant data to support your clinical decisions.

The choice to use an antimicrobial-protected catheter should be made with patients in mind—to protect and defend against CLABSI-causing pathogens.⁷

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References:

Cook TM, Harper NJN, Farmer L, et al. Anaesthesia, surgery, and life-threatening allergic reactions: protocol and methods of the 6th National Audit Project (NAP6) of the Royal College of Anaesthetists. Br J Anaesth. 2018;121(1):124-133. doi:10.1016/j.bja.2018.04.001
Toor H, Farr S, Savla P, Kashyap S, Wang S, Miulli DE. Prevalence of central line-associated bloodstream infections (CLABSI) in intensive care and medical-surgical units. Cureus. 2022;14(3):e22809. doi:10.7759/cureus.22809
Rupp ME, Lisco SJ, Lipsett PA, et al. Effect of a second-generation venous catheter impregnated with chlorhexidine and silver sulfadiazine on central catheter-related infections: a randomized, controlled trial. Ann Intern Med. 2005;143(8):570-580. doi:10.7326/0003-4819-143-8-200510180-00007
Lorente L, Lecuona M, Jiménez A, et al. Chlorhexidine-silver sulfadiazine-impregnated venous catheters save costs. Am J Infect Control. 2014;42(3):321-324. doi:10.1016/j.ajic.2013.09.022
Lorente L, Lecuona M, Jiménez A, et al. Cost/benefit analysis of chlorhexidine-silver sulfadiazine-impregnated venous catheters for femoral access. Am J Infect Control. 2014;42(10):1130-1132. doi:10.1016/j.ajic.2014.06.027
Lorente L, Lecuona M, Jiménez A, et al. Chlorhexidine-silver sulfadiazine-impregnated venous catheters are efficient even at subclavian sites without tracheostomy. Am J Infect Control. 2016;44(12):1526-1529. doi:10.1016/j.ajic.2016.04.236
Ryder MA, et al. Reduction of Extraluminal Bacterial Colonization Using Chlorhexidine Antimicrobial-coated PICC Catheters in a Clinically Simulated Ovine Model. Infusion Nurses Society Annual Convention and Industrial Exhibition; 2012.

Contraindications:

The Arrowg+ard Blue™ and Arrowg+ard Blue Plus™ Catheters are contraindicated for patients with known hypersensitivity to chlorhexidine, silver sulfadiazine and/or sulfa drugs.

Clinical assessment of the patient must be completed to ensure no contraindications exist. Arrowg+ard Blue Advance™ Catheters are contraindicated in the following areas:

Patients with known hypersensitivity to chlorhexidine
In presence of device-related infections
In presence of previous or current thrombosis in the intended vessel or along the catheterized vessel pathway

No correlation between in vitro/in vivo testing methods and clinical outcomes have currently been ascertained.

Teleflex, the Teleflex logo, Arrow, Arrowg+ard Blue, Arrowg+ard Blue Advance, and Arrowg+ard Blue Plus are trademarks of Teleflex Incorporated or its affiliates, in the U.S. and/or other countries. All other trademarks are trademarks of their respective owners. MCI-102066

Chlorhexidine Sensitivity Information

The risk is low.

What is Chlorhexidine?

The risks of CLABSIs are growing.

Power of Chlorhexidine

CLABSI Risks

Have a patient with a suspected chlorhexidine allergy?

Determined Commitment

Teleflex strives to be your trusted vascular access partner, working with you to provide accurate and relevant data to support your clinical decisions.

Would you like to download our informational material?

Contact us