Intraosseous Access

Arrow® EZ-IO® Intraosseous Vascular Access System:
A Line of Defense in Emergency Situations

In any situation where intravenous access is difficult or impossible to obtain in emergent, urgent, or medically necessary cases for up to 24 hours, the EZ-IO® System provides peripheral venous access with central venous catheter performance.1-4

The Proximal Humerus Advantage


Greater flow rate
Average flow rate of 6.3 L/hour under pressure for proximal humerus2, 7, 1 L/hour for tibia5

Reach the heart with medication or fluid in three seconds view video 2,8

Arrow® EZ-IO® System Benefits

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More than 90 case studies or clinical trials,9 learn more

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Achieves vascular access within 10 seconds10

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97% first-attempt access success rate11


Can Your Patients Afford to Wait for IV Access?

It's time to think of intraosseous access earlier.

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16 minutes

Average time needed for peripheral IV catheterization is reportedly as high as 16 minutes in patients with difficult vascular access12

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40% failure

During emergency situations, vascular access fails up to 40% of the time13

While the articles support intraosseous vascular access indications, claims and applications of Arrow® EZ-IO® Intraosseous Vascular Access System, readers should consult a physician and product labeling for proper indications, contraindications, warnings and precautions prior to use.

Potential complications may include local or systemic infection, hematoma, extravasations, or other complications associated with percutaneous insertion of sterile devices.

Rx only


  1. Compared to single lumen Central Venous Catheters (CVCs). 
  2. Based on Adult Proximal Humerus EZ-IO® insertion data.
  3. Hoskins SL, Nascimento P Jr., Lima RM, Espana-Tenorio, JM, Kramer GC. Pharmacokinetics of intraosseous and central venous drug delivery during cardiopulmonary resuscitation. Resuscitation 2011; doi:10.1016/j.resuscitation.2011.07.041. Research sponsored by Teleflex Incorporated. (preclinical study)
  4. Hoskins SL, Zachariah BS, Copper N, Kramer GC. Comparison of intraosseous proximal humerus and sternal routes for drug delivery during CPR. Circulation 2007; 116:II_993. Research sponsored by Teleflex Incorporated. (preclinical study)
  5. Based on Adult Proximal Tibial data.
  6. Philbeck TE, Miller LJ, Montez D, Puga T. Hurts so good; easing IO pain and pressure. JEMS. 2010;35(9):58-69. Research sponsored by Teleflex Incorporated.
  7. Puga T, Montez D, Philbeck T, Davlantes C. Adequacy of Intraosseous Vascular Access Insertion Sites for High‐Volume Fluid Infusion. Crit Care Med 2016; 44(12):143. Research sponsored by Teleflex Incorporated. Based on healthy volunteer study.
  8. Montez D, Puga T, Miller LJ, et al. Intraosseous infusions from the proximal humerus reach the heart in less than 3 seconds in human volunteers. Annals of Emergency Medicine. 2015;66(4S):S47. Research sponsored by Teleflex Incorporated.
  9. Internal clinical evidence summary on file.
  10. Davidoff J, Fowler R, Gordon D, et al. Clinical evaluation of a novel intraosseous device for adults: prospective, 250-patient, multi-center trial. JEMS. 2005;30(10):s20-3. Research sponsored by Teleflex Incorporated.
  11. Cooper BR, Mahoney PF, Hodgetts TJ, Mellor A. Intra-osseous access (EZ-IO®) for resuscitation: UK military combat experience. J R Army Med Corps. 2007;153(4):314-316.
  12. Leidel BA, Kirchhoff C, Bogner V, Braunstein V, Biberthaler P, Kanz K-G. Comparison of intraosseous versus central venous vascular access in adults under resuscitation in the emergency department with inaccessible peripheral veins. Resuscitation 2012;83(1):40-45.
  13. Leidel BA, Kirchhoff C, Bogner V, et al. Is the intraosseous access route fast and efficacious compared to conventional central venous catheterization in adult patients under resuscitation in the emergency department? A prospective observational pilot study. Patient Saf Surg. 2009;3(1):1-8.
Teleflex, the Teleflex logo, Arrow, EZ-Connect, EZ-IO and EZ-Stabilizer are trademarks or registered trademarks of Teleflex Incorporated or its affiliates, in the U.S. and/or other countries. MC-006531 LA EN